## Create a consensus sequence

### Description

This tool uses EMBOSS program cons or consambig to create a consensus sequence from a multiple sequence alignment. To obtain the consensus, the sequence weights and a scoring matrix are used to calculate a score for each amino acid residue or nucleotide at each position in the alignment. The highest scoring residue goes into the consensus sequence if the score is higher than a user-specified "plurality" value, otherwise, there is no consensus at that position. If ambiguous consensus sequence is selected, this tool determines which ambiguity codes match all residues or nucleotides in the input sequences at each position.

The input sequences can be in any of the EMBOSS compatible sequence alignment formats. Note that this tool reads just one input file, that should contain all the sequences to be analyzed.

For more details, please check the manual pages of cons and consambig commands.

### Output

Output is a fasta formatted sequence file.